Q: What are the increased risks for women taking estrogen plus progestin?
A: The results of a five-year study show that of every 10,000 women per year taking Prempro, there would be: 8 more cases of breast cancer, 7 more cases of heart attacks, 8 more cases of stroke, and 18 more cases of blood clots in the lungs and legs.

Q: Are there any risks that were found to be lower in women taking estrogen plus progestin?
A: The results of a recent five-year study showed that of every 10,000 women per year taking Prempro, there would be: 6 fewer cases of colon cancer; and 5 fewer cases of hip fracture.