Can Other Medicines or Foods Affect the Duragesic Skin Patch?

The Duragesic skin patch and certain other medicines can interact with each other. Tell your healthcare professional about all the medicines you take - including prescription and non-prescription medicines, vitamins, and herbal supplements - especially other medicines that make you sleepy such as:

• Other pain medicines
• Sleeping pills
• Anxiety medicines
• Antihistamines
• Tranquilizers

Do not start any new prescription medicine, non-prescription medicine, or herbal supplement while using the Duragesic skin patch until you have talked to your healthcare professional.

What Else Should I know About the Duragesic Skin Patch?

Call your healthcare professional right away if you get a fever higher than 102ºF. A fever may cause an overdose of the medicine in the Duragesic skin patch. Your healthcare professional may tell you to use a lower dose while you have a fever.

Do not use the Duragesic skin patch if the seal is broken or the patch is cut, damaged or changed in any way. Using a patch that is cut, damaged, or changed in any way can expose you to the contents of the patch, which contains a potentially fatal dose of medicine.

Do not change your dose or stop using the Duragesic skin patch unless your healthcare professional tells you to.

Do not use the Duragesic skin patch more often than prescribed.

Do not wear more than one Duragesic skin patch at a time, unless your healthcare professional tells you to do so.

After you have stopped using a patch, be sure to fold the sticky sides of the patch together and flush it down the toilet. Do not put used Duragesic skin patches in a garbage can.

If your healthcare professional tells you to stop using the Duragesic skin patch, throw away the unused packages. Open the unused packages and fold the sticky sides of the patches together, and flush them down the toilet.