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Diclofenac Overview


Call your healthcare professional immediately if you experience any of the following side effects:

  • unexplained weight gain
  • excessive tiredness
  • lack of energy
  • upset stomach
  • loss of appetite
  • itching
  • pain in the upper right part of the stomach
  • yellowing of the skin or eyes
  • flu-like symptoms
  • fever
  • blisters
  • rash
  • hives
  • swelling of the eyes, face, tongue, lips, throat, arms, hands, feet, ankles, or lower legs
  • difficulty breathing or swallowing
  • hoarseness
  • pale skin
  • fast heartbeat
  • cloudy, discolored, or bloody urine
  • back pain
  • difficult or painful urination

Are There Any Interactions With Drugs or Foods?

Diclofenac and certain other medicines can interact with each other. Tell your healthcare professional about all the medicines you take -- including prescription and non-prescription medicines, vitamins, and herbal supplements -- especially:

  • anticoagulants ('blood thinners') such as warfarin (Coumadin)
  • aspirin
  • other NSAIDS such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn)
  • or oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone)
  • angiotensin-converting enzyme (ACE) inhibitors such as:
    • benazepril (Lotensin)
    • captopril (Capoten)
    • enalapril (Vasotec)
    • fosinopril (Monopril)
    • lisinopril (Prinivil, Zestril)
    • moexipril (Univasc)
    • perindopril (Aceon)
    • quinapril (Accupril)
    • ramipril (Altace)
    • trandolapril (Mavik)
  • cyclosporine (Neoral, Sandimmune)
  • digoxin (Lanoxin)
  • diuretics ('water pills')
  • insulin and oral medication for diabetes
  • lithium (Eskalith, Lithobid)
  • methotrexate (Rheumatrex).

Unless your healthcare professional tells you otherwise, you may continue your normal diet.

Getting Legal Help

While all medications have certain anticipated side effects, a drug manufacturer has a duty to make its products as reasonably safe as possible, and to inform the medical community and the public of known risks associated with its drugs. If a manufacturer fails to do so, it can be held legally responsible if patients are injured as the result of inadequate warnings or the unreasonably dangerous nature of the drug, under a legal theory called "product liability."

If you or a loved one have experienced any dangerous symptoms or unusual medical conditions while taking diclofenac, you should first contact your doctor or other healthcare professional. You may also wish to meet with an experienced attorney to discuss your options and to protect your right to a legal remedy for any injuries caused by diclofenac use.

Go here to learn more about an attorney's role in a pharmaceutical liability case.

To find an experienced attorney, use the "Find a Lawyer" tool on the left side of this page, or click here.

See also:

Most content from the U.S. National Library of Medicine and the National Institutes of Health

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